Xanthine oxidoreductase-IN-5
Modify Date: 2024-04-06 09:15:25
Xanthine oxidoreductase-IN-5 structure
|
Common Name | Xanthine oxidoreductase-IN-5 | ||
|---|---|---|---|---|
| CAS Number | 1026652-90-3 | Molecular Weight | 323.35 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H17N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Xanthine oxidoreductase-IN-5Xanthine oxidoreductase-IN-5 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 55 nM. Xanthine oxidoreductase-IN-5 can be used for the research of acute hyperuricemia[1]. |
| Name | Xanthine oxidoreductase-IN-5 |
|---|
| Description | Xanthine oxidoreductase-IN-5 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 55 nM. Xanthine oxidoreductase-IN-5 can be used for the research of acute hyperuricemia[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 55 nM (xanthine oxidoreductase)[1] |
| In Vivo | Xanthine oxidoreductase-IN-5 (化合物 IIIa) (5 mg/kg; 口服给药) 在给药后 5 h 显示出降低急性高尿酸血症小鼠尿酸的作用[1]。 Animal Model: ICR mice (18-22 g) were induced acute hyperuricemia by injection of potassium oxonate and hypoxanthine[1] Dosage: 5 mg/kg Administration: Suspended in 0.5% CMC-Na solution for intragastric administration Result: Showed a uric acid-lowering effect from 5 h after administration. |
| References |
| Molecular Formula | C17H17N5O2 |
|---|---|
| Molecular Weight | 323.35 |