Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)

Modify Date: 2024-01-04 18:04:08

Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) Structure
Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) structure
Common Name Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)
CAS Number 1205744-09-7 Molecular Weight 689.95
Density N/A Boiling Point N/A
Molecular Formula C33H63N5O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)


Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)

  Biological Activity

Description Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C33H63N5O8S
Molecular Weight 689.95

 Safety Information

Hazard Codes Xi