B-Raf IN 8

Modify Date: 2025-08-21 10:36:21

B-Raf IN 8 structure	Common Name	B-Raf IN 8
	CAS Number	1215313-19-1	Molecular Weight	307.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₇N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of B-Raf IN 8

B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC50 of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC50 values of 9.78, 13.78, 18.52 and 29.85 µM[1].

Name	B-Raf IN 8

Description	B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC50 of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC50 values of 9.78, 13.78, 18.52 and 29.85 µM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> Raf
Target	B-Raf:70.65 ± 0. nM (IC50)
References	[1]. Thabit MG, et al. Design, synthesis and molecular modeling of phenyl dihydropyridazinone derivatives as B-Raf inhibitors with anticancer activity. Bioorg Chem. 2020 Oct;103:104148.

Molecular Formula	C₁₈H₁₇N₃O₂
Molecular Weight	307.35

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B-Raf IN 8

Use of B-Raf IN 8

Names

B-Raf IN 8 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.