Azido-PEG20-alcohol

Modify Date: 2024-01-16 10:16:23

Azido-PEG20-alcohol Structure
Azido-PEG20-alcohol structure
Common Name Azido-PEG20-alcohol
CAS Number 1637297-21-2 Molecular Weight 924.08
Density N/A Boiling Point N/A
Molecular Formula C40H81N3O20 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG20-alcohol


Azido-PEG20-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG20-alcohol

 Azido-PEG20-alcohol Biological Activity

Description Azido-PEG20-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C40H81N3O20
Molecular Weight 924.08