Boc-NH-C4-Br
Modify Date: 2024-01-11 19:54:31
Boc-NH-C4-Br structure
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Common Name | Boc-NH-C4-Br | ||
|---|---|---|---|---|
| CAS Number | 164365-88-2 | Molecular Weight | 252.149 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 308.8±25.0 °C at 760 mmHg | |
| Molecular Formula | C9H18BrNO2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 140.5±23.2 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
Use of Boc-NH-C4-BrBoc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | tert-butyl N-(4-bromobutyl)carbamate |
|---|---|
| Synonym | More Synonyms |
| Description | Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 308.8±25.0 °C at 760 mmHg |
| Molecular Formula | C9H18BrNO2 |
| Molecular Weight | 252.149 |
| Flash Point | 140.5±23.2 °C |
| Exact Mass | 251.052078 |
| PSA | 38.33000 |
| LogP | 2.78 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.473 |
| Storage condition | 2-8°C |
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R41 |
| Safety Phrases | S26-S39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2924199090 |
![4-[(2-methylpropan-2-yl)oxycarbonylamino]butyl methanesulfonate structure](https://www.chemsrc.com/caspic/281/174626-25-6.png)
| Precursor 8 | |
|---|---|
| DownStream 1 | |
CAS#:86953-79-9| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
|
H. Ina et al.
J. Org. Chem. 61 , 1023 , (1995)
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D.L. Selwood et al.
J. Med. Chem. 4 , 78, (2001)
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| 4-bromobutylamine tert-butylcarbamate |
| N-Boc 4-bromobutan-1-amine |
| tert-butyl 4-bromobutylcarbamate |
| Carbamic acid, N-(4-bromobutyl)-, 1,1-dimethylethyl ester |
| BrCH2CH2CH2CH2NHBoc |
| 2-Methyl-2-propanyl (4-bromobutyl)carbamate |
| MFCD06201020 |
| N-(4-Bromobutyl)-Carbamic Acid 1,1-Dimethylethyl Ester |
| tert-Butyl (4-bromobutyl)carbamate |