Propargyl-PEG3-CH2COOH

Modify Date: 2024-01-09 02:10:33

Propargyl-PEG3-CH2COOH Structure
Propargyl-PEG3-CH2COOH structure
Common Name Propargyl-PEG3-CH2COOH
CAS Number 1694731-93-5 Molecular Weight 246.26
Density N/A Boiling Point N/A
Molecular Formula C11H18O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG3-CH2COOH


Propargyl-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG4-CH2CO2H

 Propargyl-PEG3-CH2COOH Biological Activity

Description Propargyl-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing ProteinDegradation. J Med Chem. 2018 Jan 25;61(2):453-461.

 Chemical & Physical Properties

Molecular Formula C11H18O6
Molecular Weight 246.26
Storage condition -20°C
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