Propargyl-PEG3-bromide

Modify Date: 2024-01-04 15:51:03

Propargyl-PEG3-bromide Structure
Propargyl-PEG3-bromide structure
Common Name Propargyl-PEG3-bromide
CAS Number 203740-63-0 Molecular Weight 251.118
Density 1.3±0.1 g/cm3 Boiling Point 287.8±25.0 °C at 760 mmHg
Molecular Formula C9H15BrO3 Melting Point N/A
MSDS N/A Flash Point 115.0±21.7 °C

 Use of Propargyl-PEG3-bromide


Propargyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG3-Bromide
Synonym More Synonyms

 Propargyl-PEG3-bromide Biological Activity

Description Propargyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 287.8±25.0 °C at 760 mmHg
Molecular Formula C9H15BrO3
Molecular Weight 251.118
Flash Point 115.0±21.7 °C
Exact Mass 250.020447
LogP 0.73
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.477

 Synonyms

PROPARGYL-PEG3-BR
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