ARTD10/PARP10-IN-1

Modify Date: 2024-04-05 17:40:03

ARTD10/PARP10-IN-1 structure	Common Name	ARTD10/PARP10-IN-1
	CAS Number	1708103-76-7	Molecular Weight	248.23
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₂N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ARTD10/PARP10-IN-1

ARTD10/PARP10-IN-1 (compound 23) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 (ARTD1/PARP1) with IC50s of 1.7 μM, 1.6 μM, 0.8 μM, and 4.4 μM, respectively[1].

Name	ARTD10/PARP10-IN-1

Description	ARTD10/PARP10-IN-1 (compound 23) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 (ARTD1/PARP1) with IC50s of 1.7 μM, 1.6 μM, 0.8 μM, and 4.4 μM, respectively[1].
Related Catalog	Signaling Pathways >> Epigenetics >> PARP Research Areas >> Inflammation/Immunology Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	ARTD1/PARP1:4.4 μM (IC50) ARTD10/PARP10:0.8 μM (IC50) ARTD8/PARP14:1.6 μM (IC50) ARTD7/PARP15:1.7 μM (IC50)
References	[1]. Ekblad T, et al. Towards small molecule inhibitors of mono-ADP-ribosyltransferases. Eur J Med Chem. 2015 May 5;95:546-51.

Molecular Formula	C₁₂H₁₂N₂O₄
Molecular Weight	248.23

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ARTD10/PARP10-IN-1
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.