ARTD10/PARP10-IN-1

Modify Date: 2024-04-05 17:40:03

ARTD10/PARP10-IN-1 Structure
ARTD10/PARP10-IN-1 structure
 Common Name ARTD10/PARP10-IN-1
CAS Number 1708103-76-7 Molecular Weight 248.23
Density N/A Boiling Point N/A
Molecular Formula C12H12N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ARTD10/PARP10-IN-1


ARTD10/PARP10-IN-1 (compound 23) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 (ARTD1/PARP1) with IC50s of 1.7 μM, 1.6 μM, 0.8 μM, and 4.4 μM, respectively[1].

 Names

Name ARTD10/PARP10-IN-1

 ARTD10/PARP10-IN-1 Biological Activity

Description ARTD10/PARP10-IN-1 (compound 23) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 (ARTD1/PARP1) with IC50s of 1.7 μM, 1.6 μM, 0.8 μM, and 4.4 μM, respectively[1].
Related Catalog
Target

ARTD1/PARP1:4.4 μM (IC50)

ARTD10/PARP10:0.8 μM (IC50)

ARTD8/PARP14:1.6 μM (IC50)

ARTD7/PARP15:1.7 μM (IC50)

References

[1]. Ekblad T, et al. Towards small molecule inhibitors of mono-ADP-ribosyltransferases. Eur J Med Chem. 2015 May 5;95:546-51.  

 Chemical & Physical Properties

Molecular Formula C12H12N2O4
Molecular Weight 248.23
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Chemsrc provides ARTD10/PARP10-IN-1(CAS#:1708103-76-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ARTD10/PARP10-IN-1 are included as well.>> amp version: ARTD10/PARP10-IN-1

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