Bis-PEG2-PFP ester
Modify Date: 2024-01-11 19:05:43
Bis-PEG2-PFP ester structure
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Common Name | Bis-PEG2-PFP ester | ||
|---|---|---|---|---|
| CAS Number | 1314378-18-1 | Molecular Weight | 538.289712 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H12F10O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Bis-PEG2-PFP esterBis-PEG2-PFP ester is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Bis-PEG2-PFP ester is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. |
| Name | Bis-PEG2-PFP ester |
|---|---|
| Synonym | More Synonyms |
| Description | Bis-PEG2-PFP ester is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Bis-PEG2-PFP ester is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. |
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| Related Catalog | |
| Target |
Non-cleavable PEGs |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C20H12F10O6 |
|---|---|
| Molecular Weight | 538.289712 |
| Hazard Codes | Xi |
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| BIS-PEG2-PFP ESTER |