Bromo-PEG5-C2-acid

Modify Date: 2024-01-09 10:52:17

Bromo-PEG5-C2-acid Structure
Bromo-PEG5-C2-acid structure
Common Name Bromo-PEG5-C2-acid
CAS Number 1817735-27-5 Molecular Weight 373.24
Density N/A Boiling Point N/A
Molecular Formula C13H25BrO7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG5-C2-acid


Bromo-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Br-PEG5-acid
Synonym More Synonyms

 Bromo-PEG5-C2-acid Biological Activity

Description Bromo-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H25BrO7
Molecular Weight 373.24

 Synonyms

MFCD29042374