Bromodomain inhibitor-9

Modify Date: 2024-01-17 07:42:15

Bromodomain inhibitor-9 Structure
Bromodomain inhibitor-9 structure
Common Name Bromodomain inhibitor-9
CAS Number 1870849-34-5 Molecular Weight 484.57
Density N/A Boiling Point N/A
Molecular Formula C24H28N4O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromodomain inhibitor-9


Bromodomain inhibitor-9 is a Bromodomains inhibitor that selectively inhibits BRD4-1 (Kd: 12 nM). Bromodomain inhibitor-9 can be used in the research of diseases or conditions associated with systemic or tissue inflammation, lipid metabolism, fibrosis or chronic autoimmune diseases[1].

 Names

Name Bromodomain inhibitor-9

 Bromodomain inhibitor-9 Biological Activity

Description Bromodomain inhibitor-9 is a Bromodomains inhibitor that selectively inhibits BRD4-1 (Kd: 12 nM). Bromodomain inhibitor-9 can be used in the research of diseases or conditions associated with systemic or tissue inflammation, lipid metabolism, fibrosis or chronic autoimmune diseases[1].
Related Catalog
Target

BRD4-1:12 nM (Kd)

BRD4-2:5600 nM (Kd)

In Vitro Bromodomain inhibitor-9 (Compound 99, 1 h) inhibits LPS induced cytokines (IL12P40) release in PBMCs, with an IC50 value of 400 nM[1].
References

[1]. Gerner Seitzberg, et al. Heterocyclic compounds as inhibitors of bromodomains and their preparation. Patent WO2016016316.

 Chemical & Physical Properties

Molecular Formula C24H28N4O5S
Molecular Weight 484.57
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