LY3295668 (AK-01)
Modify Date: 2025-09-22 23:00:48
LY3295668 (AK-01) structure
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Common Name | LY3295668 (AK-01) | ||
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| CAS Number | 1919888-06-4 | Molecular Weight | 489.95 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H26ClF2N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LY3295668 (AK-01)LY3295668 is a potent, orally active and highly specific Aurora-A kinase inhibitor, with Ki values of 0.8 nM and 1038 nM for AurA and AurB, respectively. |
| Name | LY3295668 |
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| Description | LY3295668 is a potent, orally active and highly specific Aurora-A kinase inhibitor, with Ki values of 0.8 nM and 1038 nM for AurA and AurB, respectively. |
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| Related Catalog | |
| Target |
Aurora A:0.8 nM (IC50) |
| In Vitro | LY3295668 is a highly specific Aurora-A kinase inhibitor, with Ki values of 0.8 nM and 1038 nM for AurA and AurB, respectively. LY3295668, a highly specific AurA inhibitor, can kill Rb-deficient cancer cells at doses that have minimal effects on normal cells. In a kinome-wide survey, only 5 of 386 kinases are potently inhibited by LY3295668 (<10 nM)[1]. |
| References |
| Molecular Formula | C24H26ClF2N5O2 |
|---|---|
| Molecular Weight | 489.95 |
| Storage condition | 2-8℃ |