Pancreatic lipase/Carboxylesterase 1-IN-1

Modify Date: 2024-01-10 07:21:43

Pancreatic lipase/Carboxylesterase 1-IN-1 Structure
Pancreatic lipase/Carboxylesterase 1-IN-1 structure
Common Name Pancreatic lipase/Carboxylesterase 1-IN-1
CAS Number 194235-21-7 Molecular Weight 468.67
Density N/A Boiling Point N/A
Molecular Formula C30H44O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pancreatic lipase/Carboxylesterase 1-IN-1


Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A) with IC50 values of 2.13 µM and 0.055  µM against PL and hCES1A[1].

 Names

Name Pancreatic lipase/Carboxylesterase 1-IN-1

  Biological Activity

Description Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A) with IC50 values of 2.13 µM and 0.055  µM against PL and hCES1A[1].
Related Catalog
Target

IC50: 0.055  µM (hCES1A), 2.13 µM (PL), 6.02 µM (hCES2A)[1]

References

[1]. Zhang J, et al. Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1. J Enzyme Inhib Med Chem. 2022 Dec;37(1):629-640.

 Chemical & Physical Properties

Molecular Formula C30H44O4
Molecular Weight 468.67