Thalidomide-O-C8-NH2
Modify Date: 2024-01-17 05:41:29
Thalidomide-O-C8-NH2 structure
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Common Name | Thalidomide-O-C8-NH2 | ||
|---|---|---|---|---|
| CAS Number | 1957235-91-4 | Molecular Weight | 401.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H27N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-O-C8-NH2Thalidomide-O-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | Thalidomide-O-C8-NH2 |
|---|
| Description | Thalidomide-O-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C21H27N3O5 |
|---|---|
| Molecular Weight | 401.46 |
| Storage condition | 2-8°C |