m-PEG4-Br structure
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Common Name | m-PEG4-Br | ||
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CAS Number | 110429-45-3 | Molecular Weight | 271.14900 | |
Density | 1.256g/cm3 | Boiling Point | 296.3ºC at 760 mmHg | |
Molecular Formula | C9H19BrO4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 118.8ºC |
Use of m-PEG4-Brm-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency[1]. |
Name | Triethylene Glycol 2-Bromoethyl Methyl Ether |
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Synonym | More Synonyms |
Description | m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency[1]. |
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Related Catalog | |
Target |
Cleavable |
In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
References |
Density | 1.256g/cm3 |
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Boiling Point | 296.3ºC at 760 mmHg |
Molecular Formula | C9H19BrO4 |
Molecular Weight | 271.14900 |
Flash Point | 118.8ºC |
Exact Mass | 270.04700 |
PSA | 36.92000 |
LogP | 1.07750 |
Vapour Pressure | 0.00256mmHg at 25°C |
Index of Refraction | 1.454 |
Storage condition | 2-8°C |
1-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-2-methoxyethane |
Triethylene Glycol 2-BroMoethyl Methyl Ether |
2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethyl Bromide |
1-Bromo-3,6,9,12-tetraoxatridecane |