Antitumor agent-71
Modify Date: 2024-01-08 17:17:03
Antitumor agent-71 structure
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Common Name | Antitumor agent-71 | ||
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| CAS Number | 2011756-99-1 | Molecular Weight | 509.62 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H31N5O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Antitumor agent-71Antitumor Agent-71 is an antiproliferative activity antitumor agent and against tumor cell lines with IC50 values ranging from 3.98-15.70 μM. Antitumor Agent-71 is an antitumor agent that can inhibit tubulin polymerization. |
| Name | Antitumor agent-71 |
|---|
| Description | Antitumor Agent-71 is an antiproliferative activity antitumor agent and against tumor cell lines with IC50 values ranging from 3.98-15.70 μM. Antitumor Agent-71 is an antitumor agent that can inhibit tubulin polymerization. |
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| Related Catalog | |
| Target |
3.98/15.70/10.48/5.38 μM |
| In Vitro | Antitumor agent-71 (0.002-20 μM; 48 hours) inhibits the cell line HepG2, MCF-7, MIA PaCa-2, and Bel-7402 growth in a dose-dependent manner[1]. Cell Viability Assay Cell Line: HepG2, MCF-7, MIA PaCa-2, and Bel-7402[1]. Concentration: 0.002-20 μM Incubation Time: 48h Result: Showed antitumor activity against HepG2, MIA PaCa-2, MCF-7, and Bel-7402 cell lines with the IC50 values of 3.98/15.70/10.48/5.38 μM. |
| In Vivo | Antitumor agent-71 (10-20 mg/kg; intravenous injection; twice a day; 20 days) shows inhibitory effects and inhibits HepG2 cell line in nude mice[1]. Animal Model: HepG2 model BALB/c nude mice[1] Dosage: 10mg/kg, 20mg/kg Administration: Intravenous injection; twice a day; 20 days Result: Inhibited tumor growth in a dose-dependent manner. |
| References |
| Molecular Formula | C26H31N5O4S |
|---|---|
| Molecular Weight | 509.62 |