Azido-PEG4-(CH2)3OH

Modify Date: 2024-01-02 12:52:21

Azido-PEG4-(CH2)3OH Structure
Azido-PEG4-(CH2)3OH structure
Common Name Azido-PEG4-(CH2)3OH
CAS Number 2028281-87-8 Molecular Weight 277.317
Density N/A Boiling Point N/A
Molecular Formula C11H23N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG4-(CH2)3OH


Azido-PEG4-(CH2)3OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG4-(CH2)3OH
Synonym More Synonyms

 Azido-PEG4-(CH2)3OH Biological Activity

Description Azido-PEG4-(CH2)3OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C11H23N3O5
Molecular Weight 277.317
Exact Mass 277.163757
LogP -1.16
Storage condition 2-8°C

 Synonyms

AZIDO-PEG4-(CH2)3OH
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