LSD1-IN-5

Modify Date: 2024-01-10 12:12:47

LSD1-IN-5 Structure
LSD1-IN-5 structure
Common Name LSD1-IN-5
CAS Number 2035912-55-9 Molecular Weight 349.18
Density N/A Boiling Point N/A
Molecular Formula C15H13BrN2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LSD1-IN-5


LSD1-IN-5 (Compound 4e) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 121 nM. LSD1-IN-5 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1].

 Names

Name LSD1-IN-5

 LSD1-IN-5 Biological Activity

Description LSD1-IN-5 (Compound 4e) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 121 nM. LSD1-IN-5 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1].
Related Catalog
Target

IC50: 121 nM (LSD1)[1]

References

[1]. Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.

 Chemical & Physical Properties

Molecular Formula C15H13BrN2O3
Molecular Weight 349.18