Biotin-PEG6-NHS ester

Modify Date: 2024-01-16 00:25:41

Biotin-PEG6-NHS ester Structure
Biotin-PEG6-NHS ester structure
Common Name Biotin-PEG6-NHS ester
CAS Number 2055045-04-8 Molecular Weight 676.78
Density N/A Boiling Point N/A
Molecular Formula C29H48N4O12S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG6-NHS ester


Biotin-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG6-NHS ester
Synonym More Synonyms

 Biotin-PEG6-NHS ester Biological Activity

Description Biotin-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C29H48N4O12S
Molecular Weight 676.78

 Synonyms

MFCD22056308
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