Mal-amido-PEG3-acid

Modify Date: 2024-01-16 18:53:09

Mal-amido-PEG3-acid Structure
Mal-amido-PEG3-acid structure
Common Name Mal-amido-PEG3-acid
CAS Number 2055353-75-6 Molecular Weight 372.37
Density N/A Boiling Point N/A
Molecular Formula C16H24N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-amido-PEG3-acid


Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-amido-PEG3-acid

 Mal-amido-PEG3-acid Biological Activity

Description Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.

 Chemical & Physical Properties

Molecular Formula C16H24N2O8
Molecular Weight 372.37
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi