Bromoacetamido-PEG3-NH-Boc

Modify Date: 2024-04-08 17:29:21

Bromoacetamido-PEG3-NH-Boc Structure
Bromoacetamido-PEG3-NH-Boc structure
Common Name Bromoacetamido-PEG3-NH-Boc
CAS Number 1421933-39-2 Molecular Weight 413.305
Density 1.3±0.1 g/cm3 Boiling Point 543.8±50.0 °C at 760 mmHg
Molecular Formula C15H29BrN2O6 Melting Point N/A
MSDS N/A Flash Point 282.7±30.1 °C

 Use of Bromoacetamido-PEG3-NH-Boc


Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromoacetamido-PEG3 -Boc-amine
Synonym More Synonyms

 Bromoacetamido-PEG3-NH-Boc Biological Activity

Description Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 543.8±50.0 °C at 760 mmHg
Molecular Formula C15H29BrN2O6
Molecular Weight 413.305
Flash Point 282.7±30.1 °C
Exact Mass 412.120880
LogP 0.45
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.484

 Synonyms

MFCD23378554
2-Methyl-2-propanyl (14-bromo-13-oxo-3,6,9-trioxa-12-azatetradec-1-yl)carbamate
Carbamic acid, N-(14-bromo-13-oxo-3,6,9-trioxa-12-azatetradec-1-yl)-, 1,1-dimethylethyl ester
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