Fluorescein-PEG3-NH-Boc

Modify Date: 2024-01-08 08:52:05

Fluorescein-PEG3-NH-Boc Structure
Fluorescein-PEG3-NH-Boc structure
Common Name Fluorescein-PEG3-NH-Boc
CAS Number 1807534-77-5 Molecular Weight 681.753
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C34H39N3O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fluorescein-PEG3-NH-Boc


Fluorescein-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Fluorescein-PEG3-(N-Boc)-Amine
Synonym More Synonyms

 Fluorescein-PEG3-NH-Boc Biological Activity

Description Fluorescein-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C34H39N3O10S
Molecular Weight 681.753
Exact Mass 681.235596
LogP 2.92
Index of Refraction 1.650

 Synonyms

5-{[(2,2-Dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)carbamothioyl]amino}-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
MFCD23726634
Benzoic acid, 5-[(17,17-dimethyl-15-oxo-1-thioxo-5,8,11,16-tetraoxa-2,14-diazaoctadec-1-yl)amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-
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