Propargyl-PEG3-alcohol

Modify Date: 2024-01-06 18:26:29

Propargyl-PEG3-alcohol structure	Common Name	Propargyl-PEG3-alcohol
	CAS Number	208827-90-1	Molecular Weight	188.22100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₆O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Propargyl-PEG3-alcohol

Propargyl-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethanol
Synonym	More Synonyms

Description	Propargyl-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Andrew P. Crew, et al. Brm targeting compounds and associated methods of use. US20190300521A1.

Molecular Formula	C₉H₁₆O₄
Molecular Weight	188.22100
Exact Mass	188.10500
PSA	47.92000

3-Bromopropyne

CAS#:106-96-7

Triethylene glycol

CAS#:112-27-6

~73%

Propargyl-PEG3-...

CAS#:208827-90-1

Literature: Wang, Tao; Ng, David Y. W.; Wu, Yuzhou; Thomas, Jessica; Tamtran, Thuy; Weil, Tanja Chemical Communications, 2014 , vol. 50, # 9 p. 1116 - 1118