Azido-PEG2-t-Boc-hydrazide

Modify Date: 2024-01-23 08:42:36

Azido-PEG2-t-Boc-hydrazide Structure
Azido-PEG2-t-Boc-hydrazide structure
Common Name Azido-PEG2-t-Boc-hydrazide
CAS Number 2100306-56-5 Molecular Weight 317.34
Density N/A Boiling Point N/A
Molecular Formula C12H23N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG2-t-Boc-hydrazide


Azido-PEG2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG2-hydrazide-Boc

 Azido-PEG2-t-Boc-hydrazide Biological Activity

Description Azido-PEG2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H23N5O5
Molecular Weight 317.34