Azido-PEG4-hydrazide HCl

Modify Date: 2024-01-12 21:03:47

Azido-PEG4-hydrazide HCl Structure
Azido-PEG4-hydrazide HCl structure
Common Name Azido-PEG4-hydrazide HCl
CAS Number 2170240-96-5 Molecular Weight 305.33
Density N/A Boiling Point N/A
Molecular Formula C11H23N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG4-hydrazide HCl


Azido-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG4-hydrazide

 Azido-PEG4-hydrazide HCl Biological Activity

Description Azido-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H23N5O5
Molecular Weight 305.33