Axl-IN-8

Modify Date: 2024-01-03 01:38:31

Axl-IN-8 structure	Common Name	Axl-IN-8
	CAS Number	2231424-62-5	Molecular Weight	552.60
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₂₉FN₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Axl-IN-8

Axl-IN-8 (NO.1) is a potent AXL inhibitor, with an IC50 of <1 nM. Axl-IN-8 also inhibits c-MET, with an IC50 of 1-10 nM. Axl-IN-8 shows anti-proliferative activity against BaF3/TEL-AXL, MKN45, and EBC-1 cells, with IC50 values of <10, 226.6 and 120.3 nM, respectively[1].

Name	Axl-IN-8

Description	Axl-IN-8 (NO.1) is a potent AXL inhibitor, with an IC50 of <1 nM. Axl-IN-8 also inhibits c-MET, with an IC50 of 1-10 nM. Axl-IN-8 shows anti-proliferative activity against BaF3/TEL-AXL, MKN45, and EBC-1 cells, with IC50 values of <10, 226.6 and 120.3 nM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> TAM Receptor Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Met/HGFR
Target	c-Met:1-10 nM (IC50)
References	[1]. Duan Wenhu, et al. Compound having axl inhibitory activity, preparation method therefor and use thereof. WO2018121228A1.

Molecular Formula	C₃₁H₂₉FN₆O₃
Molecular Weight	552.60

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Axl-IN-8

Use of Axl-IN-8

Names

Axl-IN-8 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.