HDACs/mTOR Inhibitor 1
Modify Date: 2024-01-12 17:57:20
HDACs/mTOR Inhibitor 1 structure
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Common Name | HDACs/mTOR Inhibitor 1 | ||
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| CAS Number | 2271413-06-8 | Molecular Weight | 566.65 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H38N8O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HDACs/mTOR Inhibitor 1HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies, with IC50s of 0.19 nM, 1.8 nM, 1.2 nM and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα, respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induce tumor cell apoptosis with low toxicity in vivo[1]. |
| Name | HDACs/mTOR Inhibitor 1 |
|---|
| Description | HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies, with IC50s of 0.19 nM, 1.8 nM, 1.2 nM and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα, respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induce tumor cell apoptosis with low toxicity in vivo[1]. |
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| Related Catalog | |
| Target |
HDAC1:0.19 nM (IC50) HDAC6:1.8 nM (IC50) mTOR:1.2 nM (IC50) |
| References |
| Molecular Formula | C28H38N8O5 |
|---|---|
| Molecular Weight | 566.65 |
| Hazard Codes | Xi |
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