m-PEG8-ethoxycarbonyl--NHS ester

Modify Date: 2024-01-06 14:42:28

m-PEG8-ethoxycarbonyl--NHS ester structure	Common Name	m-PEG8-ethoxycarbonyl--NHS ester
	CAS Number	2353409-76-2	Molecular Weight	581.61
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₄₃NO₁₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of m-PEG8-ethoxycarbonyl--NHS ester

m-PEG8-ethoxycarbonyl--NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG8-ethoxycarbonyl-NHS ester

Description	m-PEG8-ethoxycarbonyl--NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₅H₄₃NO₁₄
Molecular Weight	581.61

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.