Fmoc-NH-PEG8-NHS ester
Modify Date: 2024-01-04 09:10:39
Fmoc-NH-PEG8-NHS ester structure
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Common Name | Fmoc-NH-PEG8-NHS ester | ||
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| CAS Number | 1334170-03-4 | Molecular Weight | 760.825 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C38H52N2O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Fmoc-NH-PEG8-NHS esterFmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 9H-Fluoren-9-ylmethyl {27-[(2,5-dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl}carbamate |
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| Synonym | More Synonyms |
| Description | Fmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C38H52N2O14 |
| Molecular Weight | 760.825 |
| Exact Mass | 760.341858 |
| LogP | -0.65 |
| Index of Refraction | 1.565 |
| 9H-Fluoren-9-ylmethyl {27-[(2,5-dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl}carbamate |
| Carbamic acid, N-[27-[(2,5-dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl]-, 9H-fluoren-9-ylmethyl ester |