m-PEG24-NHS ester

Modify Date: 2024-02-03 09:24:42

m-PEG24-NHS ester Structure
m-PEG24-NHS ester structure
Common Name m-PEG24-NHS ester
CAS Number 2395839-96-8 Molecular Weight 1214.39
Density N/A Boiling Point N/A
Molecular Formula C54H103NO28 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG24-NHS ester


m-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG24-NHS ester
Synonym More Synonyms

 m-PEG24-NHS ester Biological Activity

Description m-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C54H103NO28
Molecular Weight 1214.39

 Synonyms

MFCD11041155