PROTAC BRD4 Degrader-12

Modify Date: 2024-01-18 16:13:54

PROTAC BRD4 Degrader-12 Structure
PROTAC BRD4 Degrader-12 structure
Common Name PROTAC BRD4 Degrader-12
CAS Number 2417370-90-0 Molecular Weight 1306.58
Density N/A Boiling Point N/A
Molecular Formula C62H77F2N9O12S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC BRD4 Degrader-12


PROTAC BRD4 Degrader-12 (compound 9c) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively.

 Names

Name PROTAC BRD4 Degrader-12

 PROTAC BRD4 Degrader-12 Biological Activity

Description PROTAC BRD4 Degrader-12 (compound 9c) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively.

 Chemical & Physical Properties

Molecular Formula C62H77F2N9O12S4
Molecular Weight 1306.58
Storage condition 2-8°C
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