PROTAC BRD4 Degrader-12 structure
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Common Name | PROTAC BRD4 Degrader-12 | ||
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CAS Number | 2417370-90-0 | Molecular Weight | 1306.58 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C62H77F2N9O12S4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of PROTAC BRD4 Degrader-12PROTAC BRD4 Degrader-12 (compound 9c) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively. |
Name | PROTAC BRD4 Degrader-12 |
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Description | PROTAC BRD4 Degrader-12 (compound 9c) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively. |
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Molecular Formula | C62H77F2N9O12S4 |
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Molecular Weight | 1306.58 |
Storage condition | 2-8°C |