PROTAC BRD4 Degrader-5

Modify Date: 2024-01-11 16:22:15

PROTAC BRD4 Degrader-5 structure	Common Name	PROTAC BRD4 Degrader-5
	CAS Number	2409538-70-9	Molecular Weight	1016.67
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₀H₆₂ClN₉O₈S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC BRD4 Degrader-5

PROTAC BRD4 Degrader-5 is a PROTAC-based BRD4 degrader. PROTAC BRD4 Degrader-5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines[1].

Name	PROTAC BRD4 Degrader-5

Description	PROTAC BRD4 Degrader-5 is a PROTAC-based BRD4 degrader. PROTAC BRD4 Degrader-5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	BRD4
In Vitro	PROTAC BRD4 Degrader-5 (Compound1; 5-100 nM; 4 hours; MCF-7, MDA-MB-231, SK-BR-3 and BT-474 cells) treatment degrades BRD4 in cells[1]. Western Blot Analysis[1] Cell Line: MCF-7, MDA-MB-231, SK-BR-3 and BT-474 cells Concentration: 5 nM, 10 nM, 50 nM, 100 nM Incubation Time: 4 hours Result: Degradation of BRD4 in MCF-7, MDA-MB-231, SK-BR-3 and BT-474 cell.
References	[1]. Marı A Maneiro, et al. Antibody-PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4. ACS Chem Biol. 2020 Jun 19;15(6):1306-1312.

Molecular Formula	C₅₀H₆₂ClN₉O₈S₂
Molecular Weight	1016.67
Storage condition	2-8°C

DC Chemicals Limited
China
Product Name: PROTAC BRD4 Degrader-5
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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