PROTAC BRD4 Degrader-2

Modify Date: 2024-01-02 17:37:27

PROTAC BRD4 Degrader-2 structure	Common Name	PROTAC BRD4 Degrader-2
	CAS Number	2185795-53-1	Molecular Weight	757.79
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₀H₃₉N₉O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC BRD4 Degrader-2

PROTAC BRD4 Degrader-2 is an efficacious PROTAC BRD4 degrader with an IC50 of 14.2 nM against BRD4 BD1[1].

Name	PROTAC BRD4 Degrader-2

Description	PROTAC BRD4 Degrader-2 is an efficacious PROTAC BRD4 degrader with an IC50 of 14.2 nM against BRD4 BD1[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	Cereblon BRD4 BD1:14.2 nM (IC50)
In Vitro	PROTAC BRD4 Degrader-2 (Compound 17) inhibits the growth of THP-1 cell line with an IC50 of 1.83±0.016 μM[1]. Cell Proliferation Assay[1] Cell Line: Human monocyte lymphoma cell line THP-1 Concentration: 72 hours Incubation Time: 0.81-3.26 μM Result: Showd high anti-proliferative potency.
References	[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Molecular Formula	C₄₀H₃₉N₉O₇
Molecular Weight	757.79
Storage condition	2-8°C

DC Chemicals Limited
China
Product Name: PROTAC BRD4 Degrader-2
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Get all suppliers and price by the below link:

PROTAC BRD4 Degrader-2 suppliers

PROTAC BRD4 Degrader-2 price