hCAXII-IN-2

Modify Date: 2025-10-12 19:26:20

hCAXII-IN-2 structure	Common Name	hCAXII-IN-2
	CAS Number	2497504-86-4	Molecular Weight	411.84
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₈ClN₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of hCAXII-IN-2

hCAXII-IN-2 (compound 5i) is a potent human carbonic anhydrase XII (hCA XII) and hCA IX inhibitor with Ki values of 84.2 nM and 268.5 nM, respectively. hCAXII-IN-2 shows less active against hCA I and hCA II[1].

Name	hCAXII-IN-2

Description	hCAXII-IN-2 (compound 5i) is a potent human carbonic anhydrase XII (hCA XII) and hCA IX inhibitor with Ki values of 84.2 nM and 268.5 nM, respectively. hCAXII-IN-2 shows less active against hCA I and hCA II[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	Ki: 84.2 nM (hCA XII) and 268.5 nM (hCA IX)[1]
References	[1]. Pavitra S Thacker, et al. Synthesis and biological evaluation of some coumarin hybrids as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 Nov;104:104272.

Molecular Formula	C₂₁H₁₈ClN₃O₄
Molecular Weight	411.84

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