Azido-PEG4-NHS-ester
Modify Date: 2024-01-03 11:19:54
Azido-PEG4-NHS-ester structure
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Common Name | Azido-PEG4-NHS-ester | ||
|---|---|---|---|---|
| CAS Number | 1807534-82-2 | Molecular Weight | 374.346 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H22N4O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Azido-PEG4-NHS-esterAzido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 1-[(14-Azido-3,6,9,12-tetraoxatetradecan-1-oyl)oxy]-2,5-pyrrolidinedione |
|---|---|
| Synonym | More Synonyms |
| Description | Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C14H22N4O8 |
|---|---|
| Molecular Weight | 374.346 |
| Exact Mass | 374.143768 |
| LogP | -2.45 |
| 1-[(14-Azido-3,6,9,12-tetraoxatetradecan-1-oyl)oxy]-2,5-pyrrolidinedione |
| 2,5-Pyrrolidinedione, 1-[(14-azido-1-oxo-3,6,9,12-tetraoxatetradec-1-yl)oxy]- |