hiCE inhibitor-1

Modify Date: 2024-01-13 16:29:25

hiCE inhibitor-1 Structure
hiCE inhibitor-1 structure
Common Name hiCE inhibitor-1
CAS Number 2654-68-4 Molecular Weight 457.35
Density N/A Boiling Point N/A
Molecular Formula C18H14Cl2N2O4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of hiCE inhibitor-1


hiCE inhibitor-1, a sulfonamide derivative, is a selective human intestinal enzyme (hiCE) inhibitor with a Ki value of 53.3 nM. hiCE inhibitor-1 can be used to improve Irinotecan (HY-16562)-induced diarrhoea[1].

 Names

Name hiCE inhibitor-1

 hiCE inhibitor-1 Biological Activity

Description hiCE inhibitor-1, a sulfonamide derivative, is a selective human intestinal enzyme (hiCE) inhibitor with a Ki value of 53.3 nM. hiCE inhibitor-1 can be used to improve Irinotecan (HY-16562)-induced diarrhoea[1].
Related Catalog
References

[1]. Randy M Wadkins, et al. Discovery of novel selective inhibitors of human intestinal carboxylesterase for the amelioration of irinotecan-induced diarrhea: synthesis, quantitative structure-activity relationship analysis, and biological activity. Mol Pharmacol. 2004 Jun;65(6):1336-43.

 Chemical & Physical Properties

Molecular Formula C18H14Cl2N2O4S2
Molecular Weight 457.35
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