THP-PEG7

Modify Date: 2024-01-05 16:53:54

THP-PEG7 structure	Common Name	THP-PEG7
	CAS Number	42607-87-4	Molecular Weight	232.23900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₃₄O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of THP-PEG7

THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

Name	5,5-Dimethyl-4-methoxy-3-oxazolin-2-on
Synonym	More Synonyms

Description	THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Non-cleavable
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. [2]. Masahiro Tomita, et al. Antibody specifically recognizing resin plasticizer compound. WO2005105846A1.

Molecular Formula	C₁₇H₃₄O₈
Molecular Weight	232.23900
Exact Mass	232.09600
PSA	69.90000
LogP	0.90320

Hazard Codes	Xi

Precursor 0
DownStream 2
CAS#:3386-18-3 nonaethylene glycol CAS#:868594-48-3 Benzyl-PEG9-alcohol

4-methoxy-5,5-dimethyl-5H-oxazol-2-one

4-Methoxy-5,5-dimethyl-5H-oxazol-2-on

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: THP-PEG6-OH
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: THP-PEG6-OH
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: THP-PEG6-OH
Price: $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

THP-PEG7 suppliers