5(6)-Carboxyfluorescein Diacetate

Modify Date: 2025-08-25 15:05:52

5(6)-Carboxyfluorescein Diacetate structure	Common Name	5(6)-Carboxyfluorescein Diacetate
	CAS Number	124387-19-5	Molecular Weight	460.39
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₁₆O₉	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of 5(6)-Carboxyfluorescein Diacetate

5(6)-CFDA is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activity, which is require to activate its fluorescence, and cell-membrane integrity, which is required for intracellular retention of their fluorescent product.

Name	5(6)-Carboxyfluorescein diacetate
Synonym	More Synonyms

Description	5(6)-CFDA is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activity, which is require to activate its fluorescence, and cell-membrane integrity, which is required for intracellular retention of their fluorescent product.
Related Catalog	Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others
References	[1]. Yang T, et al. A novel nonradioactive CFDA assay to monitor the cellular immune response in myeloid leukemia. Immunobiology. 2013 Apr;218(4):548-53. [2]. Card SD, et al. Assessment of fluorescein-based fluorescent dyes for tracing Neotyphodium endophytes in planta. Mycologia. 2013 Jan-Feb;105(1):221-9. [3]. Fang X, et al. Bone marrow-derived endothelial progenitor cells are involved in aneurysm repair in rabbits. J Clin Neurosci. 2012 Sep;19(9):1283-6.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Dye Reagents

Research Areas >> Others

References

[1]. Yang T, et al. A novel nonradioactive CFDA assay to monitor the cellular immune response in myeloid leukemia. Immunobiology. 2013 Apr;218(4):548-53.

[2]. Card SD, et al. Assessment of fluorescein-based fluorescent dyes for tracing Neotyphodium endophytes in planta. Mycologia. 2013 Jan-Feb;105(1):221-9.

[3]. Fang X, et al. Bone marrow-derived endothelial progenitor cells are involved in aneurysm repair in rabbits. J Clin Neurosci. 2012 Sep;19(9):1283-6.

Molecular Formula	C₂₅H₁₆O₉
Molecular Weight	460.39
PSA	250.86000
LogP	7.60680
Storage condition	2-8℃

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
RIDADR	NONH for all modes of transport

Contractile activity of human follicular dendritic cells.

Immunol. Cell Biol. 92(10) , 851-9, (2014)

Follicular dendritic cells (FDCs) present antigens to B cells in the lymphoid follicle and inhibit B-cell apoptosis. In previous work, we obtained human FDC lines that allowed us to study the antigen ...

Chloroplasts extend stromules independently and in response to internal redox signals.

Proc. Natl. Acad. Sci. U. S. A. 112 , 10044-9, (2015)

A fundamental mystery of plant cell biology is the occurrence of "stromules," stroma-filled tubular extensions from plastids (such as chloroplasts) that are universally observed in plants but whose fu...

Effects of vitamin D receptor knockout on cornea epithelium gap junctions.

Invest. Ophthalmol. Vis. Sci. 55(5) , 2975-82, (2014)

Gap junctions are present in all corneal cell types and have been shown to have a critical role in cell phenotype determination. Vitamin D has been shown to influence cell differentiation, and recent ...

3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-4-carboxylic acid,3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid

5(6)-Carboxy-di-O-acetylfluorescein

3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid - 3',6'-diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-7-carboxylic acid (1:1)

Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 3',6'-bis(acetyloxy)-3-oxo-, compd. with 3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-7-carboxylic acid (1:1)

5(6)-CFDA