5(6)-Carboxyfluorescein Diacetate

Modify Date: 2024-01-02 04:17:12

5(6)-Carboxyfluorescein Diacetate Structure
5(6)-Carboxyfluorescein Diacetate structure
Common Name 5(6)-Carboxyfluorescein Diacetate
CAS Number 124387-19-5 Molecular Weight 460.39
Density N/A Boiling Point N/A
Molecular Formula C25H16O9 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of 5(6)-Carboxyfluorescein Diacetate


5(6)-CFDA is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activity, which is require to activate its fluorescence, and cell-membrane integrity, which is required for intracellular retention of their fluorescent product.

 Names

Name 5(6)-Carboxyfluorescein diacetate
Synonym More Synonyms

 5(6)-Carboxyfluorescein Diacetate Biological Activity

Description 5(6)-CFDA is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activity, which is require to activate its fluorescence, and cell-membrane integrity, which is required for intracellular retention of their fluorescent product.
Related Catalog
References

[1]. Yang T, et al. A novel nonradioactive CFDA assay to monitor the cellular immune response in myeloid leukemia. Immunobiology. 2013 Apr;218(4):548-53.

[2]. Card SD, et al. Assessment of fluorescein-based fluorescent dyes for tracing Neotyphodium endophytes in planta. Mycologia. 2013 Jan-Feb;105(1):221-9.

[3]. Fang X, et al. Bone marrow-derived endothelial progenitor cells are involved in aneurysm repair in rabbits. J Clin Neurosci. 2012 Sep;19(9):1283-6.

 Chemical & Physical Properties

Molecular Formula C25H16O9
Molecular Weight 460.39
PSA 250.86000
LogP 7.60680
Storage condition 2-8℃

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
RIDADR NONH for all modes of transport

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 Synonyms

3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-4-carboxylic acid,3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid
5(6)-Carboxy-di-O-acetylfluorescein
3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid - 3',6'-diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-7-carboxylic acid (1:1)
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 3',6'-bis(acetyloxy)-3-oxo-, compd. with 3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-7-carboxylic acid (1:1)
5(6)-CFDA