2-Propen-1-one,1-(4-methoxyphenyl)-3-phenyl-
Modify Date: 2024-01-03 17:54:29
2-Propen-1-one,1-(4-methoxyphenyl)-3-phenyl- structure
|
Common Name | 2-Propen-1-one,1-(4-methoxyphenyl)-3-phenyl- | ||
|---|---|---|---|---|
| CAS Number | 959-23-9 | Molecular Weight | 238.28100 | |
| Density | 1.114g/cm3 | Boiling Point | 397.5ºC at 760mmHg | |
| Molecular Formula | C16H14O2 | Melting Point | 101-103 °C(lit.) | |
| MSDS | N/A | Flash Point | 180.5ºC | |
Use of 2-Propen-1-one,1-(4-methoxyphenyl)-3-phenyl-4'-Methoxychalcone regulates adipocyte differentiation through PPARγ activation. 4'-Methoxychalcone modulates the expression and secretion of various adipokines in adipose tissue that are involved in insulin sensitivity[1]. |
| Name | 4'-methoxychalcone |
|---|---|
| Synonym | More Synonyms |
| Description | 4'-Methoxychalcone regulates adipocyte differentiation through PPARγ activation. 4'-Methoxychalcone modulates the expression and secretion of various adipokines in adipose tissue that are involved in insulin sensitivity[1]. |
|---|---|
| Related Catalog | |
| Target |
PPARγ[1] |
| In Vitro | 4'-Methoxychalcone (5 μM; 8 days) markedly increases the mRNA expression of adipogenic genes during adipocyte differentiation, PPARγ, aP2, FAS, adiponectin and GluT 4[1]. 4'-Methoxychalcone (5 μM; 8 days) reduces the upregulated mRNA expression of IL-6, PAI-1, and MCP-1 by TNF-α in preadipocyte 3T3-L1 cells[1]. 4'-Methoxychalcone (5 μM; 0-8 days) causes an increase in PPARγ expression during differentiation, while C/EBPβ protein expression is relatively unaffected[1]. RT-PCR[1] Cell Line: Preadipocyte 3T3-L1 cells Concentration: 5 μM Incubation Time: 0 day; 2 days; 4 days; 6 days; 8 days Result: Increased the mRNA expression of all adipogenic genes, except GluT1 in adipocyte. Western Blot Analysis[1] Cell Line: Preadipocyte 3T3-L1 cells Concentration: 5 μM Incubation Time: 8 days Result: Increased PPARγ expression in adipocyte. |
| References |
| Density | 1.114g/cm3 |
|---|---|
| Boiling Point | 397.5ºC at 760mmHg |
| Melting Point | 101-103 °C(lit.) |
| Molecular Formula | C16H14O2 |
| Molecular Weight | 238.28100 |
| Flash Point | 180.5ºC |
| Exact Mass | 238.09900 |
| PSA | 26.30000 |
| LogP | 3.59130 |
| Index of Refraction | 1.606 |
| Hazard Codes | Xi: Irritant; |
|---|---|
| Risk Phrases | 36/37/38 |
| Safety Phrases | S26-S36 |
| WGK Germany | 3 |
| HS Code | 2914509090 |
| Precursor 10 | |
|---|---|
| DownStream 7 | |
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CAS#:32664-28-1| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
| EINECS 213-495-5 |
| MFCD00008407 |
| benzylidene-4'-methoxyacetophenone |
| METHOXYCHALCONE,4' |
| 1-(4'-methoxyphenyl)-3-phenylpropenone |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 2-Propen-1-one,1-(4-methoxyphenyl)-3-phenyl-
- Price: ￥658.0/100mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2-Propen-1-one,1-(4-methoxyphenyl)-3-phenyl-
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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