PF 750

Modify Date: 2024-01-02 15:48:33

PF 750 Structure
PF 750 structure
Common Name PF 750
CAS Number 959151-50-9 Molecular Weight 345.438
Density 1.2±0.1 g/cm3 Boiling Point 582.7±32.0 °C at 760 mmHg
Molecular Formula C22H23N3O Melting Point N/A
MSDS Chinese USA Flash Point 306.2±25.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of PF 750


PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile[1].

 Names

Name N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide
Synonym More Synonyms

 PF 750 Biological Activity

Description PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile[1].
Related Catalog
Target

IC50: 16.2-595 nM (FAAH)[1].

References

[1]. Ahn K, et al. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry. 2007 Nov 13;46(45):13019-30.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 582.7±32.0 °C at 760 mmHg
Molecular Formula C22H23N3O
Molecular Weight 345.438
Flash Point 306.2±25.1 °C
Exact Mass 345.184113
PSA 45.23000
LogP 3.77
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.672

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
RIDADR NONH for all modes of transport

 Synonyms

N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide
1-Piperidinecarboxamide, N-phenyl-4-(3-quinolinylmethyl)-
N-Phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide
PF-750
Nisoxetine hydrochloride
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