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喹硫平

喹硫平用途

Quetiapine(Ketipinor)是非典型的抗精神病化合物，可作用于精神分裂，狂躁和抑郁症。

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喹硫平名称

[ CAS 号 ]:
111974-69-7

[ 中文名 ]:
喹硫平

[ 英文名 ]:
Quetiapine

[中文别名 ]:

[英文别名 ]:

[14C]-Quetiapine
quetiapina
MFCD08064204
Seroquel
UNII-BGL0JSY5SI
Co-Quetiapine
quetiapinum
Quetiapine [INN:BAN]

喹硫平生物活性

[ 描述 ]:

Quetiapine(Ketipinor)是非典型的抗精神病化合物,可作用于精神分裂,狂躁和抑郁症。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 5-HT受体

信号通路 >> 神经信号通路 >> 5-HT受体

研究领域 >> 神经疾病

[参考文献]

[1]. Sheehan DV, et al. Long-term functioning and sleep quality in patients with major depressive disorder treated with extended-release quetiapine fumarate. Int Clin Psychopharmacol. 2012 Sep;27(5):239-48.

[2]. Endicott J, et al. Effects of once-daily extended release quetiapine fumarate on patient-reported outcomes in patients with generalized anxiety disorder. Neuropsychiatr Dis Treat. 2012;8:301-311.

[3]. Lee JG, et al. Safety of quetiapine fumarate extended release in the treatment of Korean patients with acute schizophrenia. Hum Psychopharmacol. 2012 Jul;27(4):403-10. doi: 10.1002/hup.2241.

[4]. Thase ME, et al. Extended release quetiapine fumarate in major depressive disorder: analysis in patients with anxious depression. Depress Anxiety. 2012 Jul;29(7):574-86. doi: 10.1002/da.21970.

[5]. Katila H, et al. Randomized, Double-Blind Study of the Efficacy and Tolerability of Extended Release Quetiapine Fumarate (Quetiapine XR) Monotherapy in Elderly Patients With Major Depressive Disorder.Am J Geriatr Psychiatry. 2012 Jun 7.

[相关活性小分子]

喹硫平物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
556.5±60.0 °C at 760 mmHg

[ 熔点 ]:
172 - 174ºC

[ 分子式 ]:
C₂₁H₂₅N₃O₂S

[ 分子量 ]:
383.507

[ 闪点 ]:
290.4±32.9 °C

[ 精确质量 ]:
383.166748

[ PSA ]:
73.60000

[ LogP ]:
1.57

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.653

[ 储存条件 ]:
-20℃

喹硫平安全信息

[ 海关编码 ]:
2934999090

喹硫平合成路线

详细合成路线

喹硫平上下游产品

喹硫平上游产品

喹硫平下游产品

喹硫平海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

喹硫平