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凝血酶受体激活肽6

凝血酶受体激活肽6用途

TRAP-6 是蛋白酶激活受体1 (PAR1) 的激动剂。

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凝血酶受体激活肽6名称

[ CAS 号 ]:
141136-83-6

[ 中文名 ]:
凝血酶受体激活肽6

[ 英文名 ]:
TRAP-6

[英文别名 ]:

MFCD00238172
TRAP-6

凝血酶受体激活肽6生物活性

[ 描述 ]:

TRAP-6 是蛋白酶激活受体1 (PAR1) 的激动剂。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 蛋白酶激活受体(PAR)

多肽产品

研究领域 >> 炎症/免疫

[参考文献]

[1]. Tripathi T, et al. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2014 May 29;55(6):3912-21.

[相关活性小分子]

凝血酶受体激活肽6物理化学性质

[ 分子式 ]:
C₃₄H₅₆N₁₀O₉

[ 分子量 ]:
748.87000

[ 精确质量 ]:
748.42300

[ PSA ]:
334.04000

[ LogP ]:
1.83420

[ 储存条件 ]:
-20°C

凝血酶受体激活肽6MSDS

详细MSDS(安全技术说明书)

凝血酶受体激活肽6安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

凝血酶受体激活肽6文献

Clinical effects of phosphodiesterase 3A mutations in inherited hypertension with brachydactyly.

Hypertension 66 , 800-8, (2015)

Autosomal-dominant hypertension with brachydactyly is a salt-independent Mendelian syndrome caused by activating mutations in the gene encoding phosphodiesterase 3A. These mutations increase the prote...

Impact of variables of the P-selectin - P-selectin glycoprotein ligand-1 axis on leukocyte-platelet interactions in cardiovascular disease.

Thromb. Haemost. 113(4) , 806-12, (2015)

The formation of leukocyte-platelet aggregates (LPA), through the P-selectin - P-selectin glycoprotein ligand (PSGL)-1 axis, plays a pivotal role in atherothrombosis. In order to investigate the influ...

Activated platelets present high mobility group box 1 to neutrophils, inducing autophagy and promoting the extrusion of neutrophil extracellular traps.

J. Thromb. Haemost. 12(12) , 2074-88, (2014)

Increasing evidence implicates both platelets and neutrophils in the formation, stabilization, and growth of peripheral and coronary thrombi. Neutrophil extracellular traps (NETs) play a key role. The...

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