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辛弗林盐酸盐

辛弗林盐酸盐用途

Synephrine(Oxedrine)盐酸盐是生物碱,是肾上腺素受体激动剂。

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辛弗林盐酸盐名称

[ CAS 号 ]:
5985-28-4

[ 中文名 ]:
辛弗林盐酸盐

[ 英文名 ]:
Synephrine hydrochloride

[中文别名 ]:

[英文别名 ]:

UNII:EN5D1IH09S
DL-synephrine hydrochloride
EINECS 227-804-6
Synephrine HCl
MFCD00050566
Synephrine hydrochloride
Oxedrine hydrochloride
Ocuton (TN)

辛弗林盐酸盐生物活性

[ 描述 ]:

Synephrine(Oxedrine)盐酸盐是生物碱,是肾上腺素受体激动剂。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体

天然产物 >> 生物碱

研究领域 >> 神经疾病

[参考文献]

[1]. Synephrine, From Wikipedia

[相关活性小分子]

辛弗林盐酸盐物理化学性质

[ 沸点 ]:
341.1ºC at 760 mmHg

[ 熔点 ]:
147-150ºC

[ 分子式 ]:
C₉H₁₄ClNO₂

[ 分子量 ]:
203.666

[ 闪点 ]:
163.4ºC

[ 精确质量 ]:
203.071304

[ PSA ]:
52.49000

[ LogP ]:
1.83790

[ 外观性状 ]:
白色细粉末

[ 储存条件 ]:
Refrigerator

辛弗林盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DO7700000

CHEMICAL NAME :: Benzyl alcohol, p-hydroxy-alpha-((methylamino)methyl)-, hydrochloride

CAS REGISTRY NUMBER :: 5985-28-4

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H13-N-O2.Cl-H

MOLECULAR WEIGHT :: 203.69

WISWESSER LINE NOTATION :: QR DYQ1M1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 71,62,1941

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 124,231,1927

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 124,231,1927

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辛弗林盐酸盐安全信息

[ 危害码 (欧洲) ]:
Xi

[ 海关编码 ]:
2922199090

辛弗林盐酸盐上下游产品

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辛弗林盐酸盐海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%