紫云英苷

产品详情：

更新时间： 2021-08-27 12:14:36

CAS号：480-10-4

常用名： 紫云英苷

价格：
￥750.0/20mg

纯度： 98.0%

备货期： 1天

库存： 900 mg

其他详情（用途，包装）：
用途： Astragalin (kaempferol-3-O-glucoside) is a flavonoid with anti-inflammatory activity and newly found in persimmon leaves and green tea seeds.IC50 value:Target: in vitro: Astragalin nontoxic at ≤ 20 μM suppressed cellular induction of Toll-like receptor 4 (TLR4) and ROS production enhanced by LPS. Both LPS and H2O2 induced epithelial eotaxin-1 expression, which was blocked by astragalin. LPS activated and induced PLCγ1, PKCβ2, and NADPH oxidase subunits of p22phox and p47phox in epithelial cells and such activation and induction were demoted by astragalin or TLR4 inhibition antagonizing eotaxin-1 induction. H2O2-upregulated phosphorylation of JNK and p38 MAPK was dampened by adding astragalin to epithelial cells, while this compound enhanced epithelial activation of Akt and ERK. H2O2 and LPS promoted epithelial apoptosis concomitant with nuclear condensation or caspase-3 activation, which was blunted by astragalin [1]. astragalin suppressed the expression of tumor necrosis factor α, interleukin 6, and nitric oxide in a dose-dependent manner in mMECs [2]. astragalin attenuated the infiltration of inflammatory cells, the activity of myeloperoxidase (MPO) and the expression of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-1β (IL-1β) in a dose-dependent manner. Additionally, Western blotting results showed that astragalin efficiently blunt decreased nuclear factor-kappaB (NF-κB) activation by inhibiting the degradation and phosphorylation of IκBα and the nuclear translocation of p65 [3]. Astragalin significantly reduced LPS-induced expression of iNOS, COX-2 and cytokines/chemokines, and production of NO in J774A.1 mouse macrophages. Astragalin inhibited LPSinduced activation of NF-κB as indicated by inhibition of degradation of IκBα, nuclear translocation of NF-κB, and NF-κB dependent gene reporter assay [4].in vivo: Mice were injected intraperitoneally (i.p.) with lipopolysaccharide (LPS) (dose range: 5-40 mg/kg). pretreatment with astragalin can improve survival during lethal endotoxemia and attenuate inflammatory responses in a murine model of lipopolysaccharide-induced acute lung injury [4]. 物理化学性质： CAS号：480-10-4 常用中文名：紫云英苷常用英文名：Astragalin 分子式：C21H20O11 分子量：448.377 密度：1.8±0.1 g/cm3 沸点：823.2±65.0 °C at 760 mmHg 熔点：223-229ºC 闪点：291.6±27.8 °C 储存条件：?20°C

供应商信息：

公司名：上海源叶生物科技有限公司

认证状态： 未认证供应商

商品数： 5711件

电话： 61559134

地址： 上海市松江区长塔路465号6幢

地区： 上海市松江区

联系人： 何喜莲

联系人电话： 15921386130 021-61559134

邮件：3285254746@qq.com

网址：http://www.shyuanye.com

主要市场：国内

年贸易额：￥1000万-5000万

外贸占销售比例：

主要合作伙伴：

公司介绍：
上海源叶生物科技有限公司是一家专门从事生物技术相关产品研发和销售的综合性生命科学公司，在全体员工的不懈努力和广大客户的大力支持下，公司迅速成长为一家拥有生物试剂部、实验部、生命科学仪器部以及技术服务部等部门的高新技术企业。公司地址：上海市杨浦区黄兴路1999号2号楼8E 我们的理念: 客户至上、服务至真；质量第一、诚信为本

其他供应商价格：

2024-09-29 价格：￥需询单紫云英苷

2022-02-19 价格：￥551.9 山萘酚3-葡萄糖苷

2025-09-17 价格：￥需询单 5,7-二羟基-2-(4-羟基苯基)-3-(((2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)-4H-苯并吡喃-4-酮

2025-12-29 价格：￥需询单紫云英苷

2021-02-06 价格：￥1939.0 astragalin

2017-10-03 价格：￥需询单紫云英苷

2024-01-09 价格：$需询单 TIANFU-CHEM - ASTRAGALIN

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紫云英苷价格

紫云英苷

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