Tetrahedron Letters

A mild Boc deprotection and the importance of a free carboxylate

A Thaqi, A McCluskey, JL Scott

Index: Thaqi, Ali; McCluskey, Adam; Scott, Janet L. Tetrahedron Letters, 2008 , vol. 49, # 49 p. 6962 - 6964

Full Text: HTML

Citation Number: 23

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... We report a facile and rapid removal of Boc protecting groups using microwave heating in H 2 O, with deprotection only requiring a free carboxylic acid group in the starting material. Unlike previous approaches, no additional reagents are required. ... Boc-deprotection of substances ...