CCR1 antagonist 1
Modify Date: 2024-01-04 13:26:24
CCR1 antagonist 1 structure
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Common Name | CCR1 antagonist 1 | ||
|---|---|---|---|---|
| CAS Number | 1010073-75-2 | Molecular Weight | 451.909 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 778.4±60.0 °C at 760 mmHg | |
| Molecular Formula | C22H22ClN7O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 424.6±32.9 °C | |
Use of CCR1 antagonist 1CCR1 antagonist 1 is an antagonist of CCR1, with anti-inflammatory activity. |
| Name | CCR1 antagonist 1 |
|---|---|
| Synonym | More Synonyms |
| Description | CCR1 antagonist 1 is an antagonist of CCR1, with anti-inflammatory activity. |
|---|---|
| Related Catalog | |
| Target |
CCR1 |
| In Vitro | CCR1 antagonist 1 shows potent activities in the chemotaxis assay, with IC50 < 100 nM[1]. |
| In Vivo | In vivo, CCR1 antagonist 1 has in vivo anti-inflammatory activity and has superior pharmacokinetic properties[1]. |
| References |
[1]. Compounds for the treatment of osteoporosis and cancers. US 20100113472 A1 |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 778.4±60.0 °C at 760 mmHg |
| Molecular Formula | C22H22ClN7O2 |
| Molecular Weight | 451.909 |
| Flash Point | 424.6±32.9 °C |
| Exact Mass | 451.152344 |
| LogP | 1.24 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.724 |
| 1-[4-(4-Chloro-3-methoxyphenyl)-1-piperazinyl]-2-[3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]ethanone |
| Ethanone, 1-[4-(4-chloro-3-methoxyphenyl)-1-piperazinyl]-2-[3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]- |
| 22PQS5K5TY |
| CCX-354 |