Cbz-NH-PEG1-CH2CH2COOH

Modify Date: 2024-01-10 11:16:31

Cbz-NH-PEG1-CH2CH2COOH Structure
Cbz-NH-PEG1-CH2CH2COOH structure
Common Name Cbz-NH-PEG1-CH2CH2COOH
CAS Number 1205751-19-4 Molecular Weight 267.28
Density N/A Boiling Point N/A
Molecular Formula C13H17NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cbz-NH-PEG1-CH2CH2COOH


Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Cbz-NH-PEG1-CH2CH2COOH
Synonym More Synonyms

 Cbz-NH-PEG1-CH2CH2COOH Biological Activity

Description Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C13H17NO5
Molecular Weight 267.28

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD14582436