NH-(PEG4-acid)2

Modify Date: 2024-01-09 14:52:07

NH-(PEG4-acid)2 Structure
NH-(PEG4-acid)2 structure
Common Name NH-(PEG4-acid)2
CAS Number 2055041-59-1 Molecular Weight 513.58
Density N/A Boiling Point N/A
Molecular Formula C22H43NO12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH-(PEG4-acid)2


NH-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name NH-bis(PEG4-acid)

 NH-(PEG4-acid)2 Biological Activity

Description NH-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H43NO12
Molecular Weight 513.58
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