Metallo-β-lactamase-IN-3

Modify Date: 2024-01-06 12:39:34

Metallo-β-lactamase-IN-3 structure	Common Name	Metallo-β-lactamase-IN-3
	CAS Number	128294-71-3	Molecular Weight	225.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₁NO₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Metallo-β-lactamase-IN-3

Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-3 shows high activity against VIM-1 and NDM-1, with IC50 of 0.6 and 1.0 μM, respectively. Metallo-β-lactamase-IN-3 does not show inhibition of IMP-7[1].

Name	Metallo-β-lactamase-IN-3

Description	Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-3 shows high activity against VIM-1 and NDM-1, with IC50 of 0.6 and 1.0 μM, respectively. Metallo-β-lactamase-IN-3 does not show inhibition of IMP-7[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 0.6 ± 0.0 μM (VIM-1), 1.0 ± 0.4 μM (NDM-1), > 10 μM (IMP-7)[1]
References	[1]. Kaya C, et al. N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases. J Med Chem. 2022 Mar 10;65(5):3913-3922.

Molecular Formula	C₁₀H₁₁NO₃S
Molecular Weight	225.26

Metallo-β-lactamase-IN-3

Use of Metallo-β-lactamase-IN-3

Names

Metallo-β-lactamase-IN-3 Biological Activity

Chemical & Physical Properties