Metallo-β-lactamase-IN-4

Modify Date: 2024-01-02 17:25:23

Metallo-β-lactamase-IN-4 Structure
Metallo-β-lactamase-IN-4 structure
Common Name Metallo-β-lactamase-IN-4
CAS Number 2711044-25-4 Molecular Weight 302.37
Density N/A Boiling Point N/A
Molecular Formula C10H14N4O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Metallo-β-lactamase-IN-4


Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor, with IC50 values of 0.5 μM (VIM-1), 2.1 μM (NDM-1), and 3.3 μM (IMP-7), respectively[1].

 Names

Name Metallo-β-lactamase-IN-4

 Metallo-β-lactamase-IN-4 Biological Activity

Description Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor, with IC50 values of 0.5 μM (VIM-1), 2.1 μM (NDM-1), and 3.3 μM (IMP-7), respectively[1].
Related Catalog
Target

IC50: 0.5 ± 0.0 μM (VIM-1), 2.1 ± 0.1 μM (NDM-1), 3.3 ± 0.4 μM (IMP-7)[1]

References

[1]. Kaya C, et al. N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases. J Med Chem. 2022 Mar 10;65(5):3913-3922.

 Chemical & Physical Properties

Molecular Formula C10H14N4O3S2
Molecular Weight 302.37